Arthritis Drugs May Trigger Shingles

Because arthritis affects so many people as they age, this finding is important for health practitioners to add to their diagnostic radar screens. This is particularly true for those who deal primarily with musculoskeletal conditions.

Patients with rheumatoid arthritis (RA) undergoing treatment with agents such as Enbrel (etanercept), Remicade (infliximab) or Humira (adalimumab) appear to have a significantly increased risk for developing shingles.

The incidence of shingles among patients on anti-tumor necrosis factor (TNF) treatment was 1.6 per 100 patient-years, compared with an incidence of 0.8 per 100 patient-years among those receiving traditional disease-modifying anti-rheumatic drugs (DMARDs), according to Kimme L. Hyrich, MD, of the University of Manchester in England, and colleagues.